| ecp | Ettercap Packet Log |
| ecr | Ecrypt Encrypted File |
| ecryptfs | eCryptfs Data |
| ecs | F-Secure Easy Clean Selection Data |
| ecu | TunerPro ECU Configuration |
| ecv | NETSCAN Vertex Search Results |
| ecx | EccoPro Corrupted Database |
| ed2 | CHARMM ED2 Data |
| ed3 | CHARMM ED3 Data |
| edat | E-Prime E-DataAid 1.x File |
| edat2 | E-Prime E-DataAid 2.x File |
| edb | Act! E-Mail Database |
| edb | EstImage Database |
| edb | Microsoft Exchange Database |
| ede | Edraw Max Element Data |
| edf | Altera EDIF Input File |
| edf | DrumBeat Component Data |
| edf | eMemoPad Data |
| edf | ESRF Data Format |
| edf | MicroEMACS Spelling Dictionary Data |
| edf | Workshare Synergy EDF Data |
| edf2 | EEGLAB Data Set |
| edfx | Estimator.NET Estimate |
| edgx | Microvellum Edgeband File |
| edh | HRV Edit Data |
| edh2 | HRV Edit Data |
| edi | ENVI-met Information File |
| edi | GROMACS Essential Dynamics Information |
| editma | Autodesk Maya 3D Offline ASCII Scene |
| editmb | Autodesk Maya 3D Offline Binary Scene |
