| emrg | E-Prime E-Merge 1.x File |
| emrg2 | E-Prime E-Merge 2.x File |
| ems | eMachineShop Data |
| emu | EMU Speech Database |
| emulecollection | eMule Data |
| enb | EverNote Database |
| enc | Uuencoded Data |
| encr | TI bqEASY Data Flash RAW |
| end | Tinker End File |
| ene | GROMACS Binary Energy File |
| enex | EverNote XML Archive |
| enf | EndNote Filter Data |
| enh | CRiSP Harvest Model Enhancement File |
| enk | Sybase Enterprise Portal Security Key |
| enl | EndNote Library Data |
| enlx | EndNote X Compressed Library Data |
| enm | eNewsletter Manager Message Data |
| eno | FruitfulTime TaskManager Encrpted Notes |
| enp | EndNote Preferences |
| enq | EndNote Saved Search |
| enr | EnRoute v2 Toolpath Data |
| enref | EverNote Food Data |
| ens | EndNote Style |
| enw | EndNote Import Data |
| enz | EndNote Connection Data |
| eo1 | MPE+ EO1 Data |
| eoc | EncryptOnClick Encrypted File |
| eoff | Exocad 3D Library |
| eom | EON Studio Mobile Prototype Library |
| eon | Strange Eons Data |
