| sep | ChemSep Separation Case Data |
| sep | SEEP/W Data |
| sep | SimEnhancer Profile |
| sep | SWAT Septic Input Data |
| seq | CYANA Sequence File |
| seq | Life Forms Studio Sequence Data |
| seq | SAM sampleseqs Sequence Data |
| seq | Tinker Sequence |
| seq | Workswell Recorded Thermal Sequence |
| seq | XtalView Xfit Sequence Data |
| seq | ZOOM MRS-802 Sequence Data |
| seqbac | SEQ Backup Data |
| ser | Noptel NOS Statistics Series Data |
| server | Bonobo Activation API Data |
| server | MySQL Server Script |
| serverdef | Eclipse WTP Server Definition Data |
| ses | Adobe Audition v2 Session |
| ses | DynaComm Terminal Session Data |
| ses | Hummingbird Exceed X-Session Data |
| ses | MSC Patran Session Data |
| ses | SciTE Session Data |
| ses | SPECCTRA Session File |
| ses | Zemax Session Data |
| sess | PHP Session Data |
| session | Mozilla Firefox Session Data |
| sesx | Adobe Audition Session |
| set | BPM Studio Encrypted User Information |
| set | Corel Painter Settings Data |
| set | Mastercam Setup Sheet Template |
| set | PLINK END-terminated Variant Set Membership List |
