| ses | Adobe Audition v2 Session |
| ses | SPECCTRA Session File |
| sesx | Adobe Audition Session |
| set | PLINK END-terminated Variant Set Membership List |
| sew | Janome Stitch-based Embroidery Data |
| sez | SEEP/W ZIP Compressed Data |
| sf | StatGraphics Centurion Data |
| sf2 | SAS Consolidation Database |
| sf3 | StatGraphics Centurion Data |
| sf6 | StatGraphics Centurion Data |
| sf7 | SAS Consolidation Database |
| sfc | SNES ROM Image SMC |
| sfcache | Microsoft Windows ReadyBoost File |
| sfera | Sfera 360 File |
| sfl | Verity Server Standard Fields File |
| sfm | DartPro 98 Audio Tree |
| sfo | CuteFTP Search |
| sfp | System File Protection Database |
| sfr | Mail.dat Special Fees File |
| sft | Microsoft App-V Application |
| sft2 | Vegas Pro Custom Rendering Template |
| sfx | StatGraphics Centurion Data |
| sg2 | SEG-2 Data File |
| sg3 | ChessDB Game Data |
| sg4 | Scid Game Database |
| sgb | Songsheet Generator Songbook |
| sgf | Smart Game Format Data |
| sgn | Slax Livecd Signature File |
| sgr | SGR Genome Data |
| sgs | Sansgui Schema Definition File |
