| emo | Miranda IM Emotions |
| emodel | Delcam PowerSHAPE-E Model |
| emp | eSignal Market Profile Data |
| emp | EVEMon Skill Plan |
| emp | Medlin Payroll Software Employee Data |
| emrg | E-Prime E-Merge 1.x File |
| emrg2 | E-Prime E-Merge 2.x File |
| ems | eMachineShop Data |
| emsg | SendSafe Saved E-message Data |
| emt | Unreal Engine Emitter Data |
| emu | EMU Speech Database |
| emu | IRMA 3270 Emulation Setup Data |
| emulecollection | eMule Data |
| en2 | Articulate Engage Compressed Data |
| enb | eNotebook Notebook Data |
| enb | EverNote Database |
| enbx | EduNetworkBuilder Network Data |
| enc | Uuencoded Data |
| enc | Yahoo! Messenger Encrypted Messages Data |
| enc1 | Kaspersky Anti-virus Log |
| encr | TI bqEASY Data Flash RAW |
| encrypted | HandyBits EasyCrypto Encrypted Data |
| end | CorelDraw Arrow-head Definition Data |
| end | Tinker End File |
| ene | GROMACS Binary Energy File |
| enex | EverNote XML Archive |
| enf | EndNote Filter Data |
| enff | Extended Neutral File Format Data |
| enfpack | Enfocus PitStop Package |
| engd | ANSYS ENGD Data |
