| cr4 | STABCAL Calculation Data |
| cram | CRAM Data |
| crash | Steam Crash Data |
| crashed | AbiWord Crash-Saved Document |
| crate | Serato DJ Crate Data |
| crc32 | CRC32 Checksum |
| crd | CARE-S InfoWorks Catchment Runoff Data |
| crd | Carlson 2016 Coordinate Data |
| crd | CHARTrunner Dashboard |
| crd | MODELLER Atom Coordinates CHARMM Data |
| crdb | Carlson 2016 Coordinate Database |
| crds | Windows CardSpace Backup |
| creole | Creole Source Code |
| crf | Cal3D Binary Materials Data |
| crf | MOUSE Runoff Data |
| crf | Sierra Print Artist Craft Data |
| crg | OpenCRG Data File |
| cri | PLS-CADD Criteria |
| cri | WaterGEMS Criticality Analysis Results Data |
| crl | Certificate Revocation List |
| crld | Clicker Crick Resource Library Data |
| crm | WRAP Conditional Reliability Modeling Data |
| crmlog | Microsoft Windows COM+ CRM Log |
| cro | AquaCrop Crop Data |
| cro | CropWat Data |
| crossdb | MixVibes Cross DJ Collection Data |
| crossmedia | MixVibes Cross DJ Media Data |
| crpd | Microsoft Windows SignTool Data |
| crpt | Cryptosaurus Encrypted File |
| crq | Blackboard Course Requests |
