| sed | IExpress Self Extraction Directive Data |
| set | General Settings File |
| set | SmartCAM Connection Settings File |
| settings | Fusion Settings Data |
| settings | General Configuration |
| sfpreset | Sony Preset Manager Preset |
| sfs | Sibelius Configuration File |
| sgc | Secure SnapGear Router Configuration |
| shed | Shed Configuration |
| shi | Simple Help Editor Settings |
| shortcut | Asutype Shortcut Data |
| sif | Windows NT Setup Information File |
| siz | Oracle 7 Configuration Data |
| skt | Lightwave 3D Skytracer Settings |
| sldreg | SolidWorks Saved Settings |
| slip | Embarcadero License Configuration |
| sll | SpectraLayers Pro Layout Settings |
| slt | K-Meleon Browser Settings Data |
| smartftp | SmartFTP Configuration Data |
| smn | SetEdit Menu Configuration |
| smprf | System Mechanic Windows Startup Profile |
| smr | Smedge2 Job Settings |
| snagprof | SnagIt Profile Data |
| sno | Starry Night Pro Presets |
| sob | OpenOffice.org Configuration File |
| soc | OpenOffice.org Configuration File |
| sod | OpenOffice.org Configuration File |
| soe | OpenOffice.org Configuration File |
| sog | OpenOffice.org Configuration File |
| soh | OpenOffice.org Configuration File |
