| son | SBStudio II Song |
| sonic | Sonic Arranger Audio |
| sop | NOTE Music Tracker Song |
| sou | SBStudio II Sound File |
| sou | SoundBlaster Studio Audio Data |
| sound | Macintosh Sound Resource |
| sox | SoX Uncompressed PCM Audio |
| spc | SpchComp Encoded Speech Data |
| spc | Super Nintendo Audio Data |
| sph | HTK NIST SPHERE Data |
| spj | Digitrax SoundFX Project |
| spl | Digitrakker Music Sample |
| spm | StoneTracker Music Module |
| sppack | SPPack Sound Sample |
| sps | StoneTracker Audio Sample |
| spu | Sony Playstation Audio Data |
| spx | Speex Compressed Audio |
| sq | Sony Playstation 2 SCEI Sequence |
| sqt | Technics SX-KN6000 Sequence Data |
| sri | Dragon NaturallySpeaking Audio File |
| srt | Siemens C60 Mobile Phone Ringtone |
| sseq | Nintendo DS Sound Data |
| ssf | Sega Saturn Audio Data |
| ssnd | Synclavier Sound |
| stem | Native Instruments Stems Audio Data |
| stk | Soundtracker Music |
| stm | Scream Tracker Module |
| strm | Nintendo DS Audio Stream |
| struma | Strum Acoustic GS-1 Exchange Data |
| strume | Strum Electric GS-1 Exchange Data |
